# Single-cell RNA sequencing of terminal ileal biopsies identifies signatures of Crohn’s disease pathogenesis

> **Open Intelligence Dossier** · First detected: 2026-06-16 09:07 UTC · Category: Health

## Executive Summary
12 news sources are covering this Health story right now — PULSE is tracking how fast it spreads.

## Intelligence Brief
"Single-cell RNA sequencing of terminal ileal biopsies identifies signatures of Crohn’s disease pathogenesis" is generating significant coverage in the Health category, with 14 articles from 12 distinct sources tracked by PULSE so far.


Outlets currently covering the story include Technology Networks, Scientific Frontline, Genetic Engineering and Biotechnology News and Medical Xpress. PULSE measures a story's velocity from how quickly new articles appear and how many independent newsrooms join the coverage.


This brief was generated by PULSE's extractive engine from coverage metadata only. The latest headlines from every source are listed below; the velocity chart shows how the story is developing in real time.

## Multi-Source Evidence Table
| Source Outlet | Headline | Verification URL |
|---|---|---|
| Technology Networks | Molecular Changes Persist After Inflammation Resolves in Crohn’s Disease | [Source Link](https://news.google.com/rss/articles/CBMiyAFBVV95cUxQOEJXck5Icm81REdpZXRqMzBOUnpIeW1xZlJGTWxPQXZuNFJWMG1sWTNjbFFoN3gzOENObDZPNWs2MEYtczk4czEzd3pFRmNxM1FyVFBfcUtDSzc5dDFJdUVhbGNZcVFHY056SE1Mek8zYkFUZmw0Tnlaamo3aXJwS2FvTHZMM2F4WGR1N2ZNRlNmSVQ4dXhicG5zZzZKUnlTZzFVT3VhckhFYmpaUG82anNQMEVvWDMxclI0RWh4Rkg5eUE1aWxRRg?oc=5) |
| Scientific Frontline | GALT Immune Cell Mapping & Ulcerative Colitis | [Source Link](https://news.google.com/rss/articles/CBMiXEFVX3lxTE1xWkUzUVIwSWhjMzBqSlV0OUV5V255THZLVVZNeUhVRzZacTR6bXktZmtvOU1jaTJ2VDNSaENNLVBQVFBBZjJManhFZnN5djVRbmEzZjRYSjZULWF1?oc=5) |
| Technology Networks | Molecular Changes Persist After Inflammation Resolves in Crohn’s Disease | [Source Link](https://news.google.com/rss/articles/CBMiywFBVV95cUxQNklQUVQtdm0xS3V1c29pajNIdVNBdjRNa0pRQmJrUnNfNjFOWFJ6NjRtUlk3eHVmZHMtSEhBSXBJZDJYVFc3cnBmZ3FfeVhOaEgyNXZsbDNIZDBqN3JyT2hhczgzTHU4bVdYVGx0UkMzX3BoLTZ0d3MyOFpHcEJIbV9weUx3NExQOVdIbjJ0ekhGckxMekxaaFh0MVdTdDR2cEN6WU84azE3LTRNMUFiVkZuQzhDc1RDT2FkWDZmLUdCRVlUeTRyN0hCVQ?oc=5) |
| Genetic Engineering and Biotechnology News | Single-Cell RNA Sequencing Reveals Gene Activity Changes in Crohn’s Disease | [Source Link](https://news.google.com/rss/articles/CBMizAFBVV95cUxOMUJaYlQyb2RHaXZ0aTZrREFjVjRaX09pS3FXSm1wM2U4ZjlDSmxtNFV3M29RbnM4eURDTV9lZDFtSjBFc3JZeXFtempieWM0VnVrZ2tNWnN0R1FOTnF2UFVlYnRDZXdVMk5Rd0dBSFM3S1JpaUhDZFloa05YS0J6a2pOQWl2UUJ0VFVocUI3SGxnLUR0UEpIdUFfVU9mZjRtcjdmWDFnb3pIYldyWmc3dDNkell5Z0ZfWFl4enJ6QVQyYzdOWXQ5M09GZnA?oc=5) |
| Medical Xpress | Immune cell circuit restores barrier function in inflammatory bowel disease | [Source Link](https://news.google.com/rss/articles/CBMihwFBVV95cUxQaXpaNWVXRWduM01HNk1pcWE1VTZlSUJZMzBxR255Z0dGYkcxMy1vOTQ4eWZ3WnpYQTl5UzRLTklIbDgxeHYwZnd3WUVMbnc3REk0Q01EUkxwNU03QjVQQWxCOVJGZEd5ajdfYjMtSGFhcjNRVTNSamhJSDFNb09jbXp5dEMxckU?oc=5) |
| Technology Networks | Molecular Changes Persist After Inflammation Resolves in Crohn’s Disease | [Source Link](https://news.google.com/rss/articles/CBMivgFBVV95cUxPYmVENmE5dzJFUkNyUkItN0VWOGdFSVlJRWxBS0IwVk4yaU9FeElTSXdJX0xOV0VORFFsT3NMSHJSWkJDLWJvYlRtNmNqOFktelVod2NlMzJQenZ0ZE85enNDTUJVb3p2MzlWd0tDX2dXa2hCTU0tZ0ZxMGQxUHFQS2tDbnVScVdZMXhyRXpqUjB3a2pWd0lxbVNScmhiOUp4Sno5dmhqRW45WWFQbDV2Y1RaZ05jR0tGb1A1RGZB?oc=5) |
| Northwestern University | Immune Cell Circuit Restores Barrier Function in IBD | [Source Link](https://news.google.com/rss/articles/CBMipgFBVV95cUxONGtaRWZiUDF4Qmg2S29RUmN6RHJuNnpHLWJQU2U1d2g5dHZrVnlvVmxQNXBneXdvaExpRThQaWRBX2ppV1RPSG1aMlBzbzNXVzM2YXlQaHJQOW9OLXUyZ0ZsdUhGdUE5dkl1MXdodVZsUmpPOERwck5nMVhwRmhzTlUzQm5SWWxpQU5icjdpZ3ZIanl0aUtHOFlFa1V6LVRqdlBBdWVR?oc=5) |
| King's College London | Mapping immune cell interactions in gut tissue reveals changes in ulcerative colitis | [Source Link](https://news.google.com/rss/articles/CBMisAFBVV95cUxNSFdFNUVyYVJrSFEtbjJjWUlzSS14cG5CVGZoR0JTQVpqUVNVTDBLaWNCdkx6SzdLMGg1S2syY1M4MGtQc3dLdnJlSEFEZEF3RkJDV211ckdKaVpnTzNsdG55cVhZVjlQU2h0VnFHcVVRRHJZcHZXWXlXSHk4cGJ4WkFQckNEazZFWGdaQi1UNW5BQ05uWEV3M0tYd1lVakZTN2FkN2hmcGhBQVNZTTR3Sg?oc=5) |
| Mirage News | Gut Immune Cell Map Unveils Ulcerative Colitis Changes | [Source Link](https://news.google.com/rss/articles/CBMiigFBVV95cUxOMFRlOGJjV1hrSENDQlBFZHIxLS1Va0lZWHUxc0RNNGJTVmVCOU0taFRzVklVcU9GQVBpTlVjazJlOW14aTVsX05wRUhzVnZwMzNWX0Rjb081WlltN0QzU2c4Y1RiSDJvNzF4RXh4TkxaRkxHaWViZzlxOUZ5RkxyenNnOUhNTTJvNGc?oc=5) |
| Glasgow Live | 'Bouncer' immune cell discovered that fights Crohn's disease and IBD | [Source Link](https://news.google.com/rss/articles/CBMikgFBVV95cUxPaVdPdzJDNlFPV0kyT2R2VzFoRFhQa3NRR21uT09uWWREU1RWQUVVbnVwa1FpbF9KVHQ0RUNkdHVhTnFSUzl2WDdEWVZLOGNjaFpRcGhmZVdVX1JpTkdRdllYOVFzSE5kUkkxakNyMGdiV3U4VWZsZHAxOTJKVGxhMFZXWnNiRmhKRW5SMXhqLWF3Zw?oc=5) |
| National Institutes of Health (.gov) | NIH researchers identify regulatory cells that shield against inflammatory bowel disease | [Source Link](https://news.google.com/rss/articles/CBMiyAFBVV95cUxPOEM0NklqNFRFQUR4Ynk1blhsMGJqYXR4TjEwaUlOUEx5OWNIaEN1TWItWG14NnJsM1ZBWGx6cnZOWVBGajM3Qms2cDRGX21zeUI2ak9CdVhwYkFILUwyTFdWSWdpcU5zZmdpNWw3amhyRl9TSU1EeXFMcUpEaVNlWFcwa3hvMlF0V0thamczLWU0N01UNFIxUVpSUnVGVlVydzZVME1MRGxOUUVTam5nTjZrdmI5a0l0UHN4cmcyMUd6bEZMZ0JybA?oc=5) |
| News-Medical | Gut cell study discovers lasting molecular scars of Crohn's disease | [Source Link](https://news.google.com/rss/articles/CBMitAFBVV95cUxQNTlZeDdLNVR3WGVkODhuMlFBNDMxbnZXWENWdkNPU3J1NlU5RjRQNm5QNUFsVGt1eGpaUlZjNE9hMDdqSDEybkdMbnA4bW9NLUlHQkQzaVJ3TzlPS3JldzZvNTQyMVVLNlBlNG9HS1A5REh3UkFjcHJJUHNOR3FFY2Q2ekpoUVAxVU1JYTFHX2g4TE9NVFJuSGFLRzQ1dVdLOFh1eDZzNVAtNUpOdFlkd0lqaXg?oc=5) |
| Cambridge News | Mystery immune cell that fights IBD has been discovered | [Source Link](https://news.google.com/rss/articles/CBMimAFBVV95cUxNSTJhbEhMbmJvcWNPYTZQX1JqQjk2eUlVY05oWnJtYmIwd1Fxb2hFWGJURDJvQ21ZZHg5QzZrV0U0NnZEV0FpSi1ZQXhmeVBGZ3lWS2w2WUVKeVVVUjcyMEdBcDBDUDJHZmZjeGZ5dXZPNXBGN0UtQ2xYRFNETGpmYmZCcEhQMDBYZ3FlWGpuNjZOZmx3ejlmYw?oc=5) |
| Nature | Single-cell RNA sequencing of terminal ileal biopsies identifies signatures of Crohn’s disease pathogenesis | [Source Link](https://news.google.com/rss/articles/CBMiX0FVX3lxTFBsOElkYzBwQWxsSmpaZ0trZUhERGNvbDF2VzFyYTFqVXk3UXVkWEx2VE45OXVBaVFod3J5M3R6SlRJTmNJdFNzdVplZjFuNlAxUVpaYlcxQ05aM0xCcFFn?oc=5) |

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*Canonical Source: https://pulse.byoviral.com/trend/2026-06-16/single-cell-rna-sequencing-of-terminal-ileal-biopsies-identifies-signatures-of*