# Northwestern performs rare quadruple-organ transplant on woman who previously had lung transplant

> **Open Intelligence Dossier** · First detected: 2026-07-14 19:07 UTC · Category: Health

## Executive Summary
Northwestern Medicine has performed a first-of-its-kind quadruple-organ transplant for a woman with cystic fibrosis who had previously received lung transplants.

## Intelligence Brief
Northwestern Medicine has completed a rare medical procedure involving a quadruple-organ transplant for a patient named Elizabeth Wehrle. According to reports from ABC7 Chicago and the Chicago Sun-Times, the patient suffers from cystic fibrosis. This specific operation is identified as the first known quadruple-organ transplant that involved the retransplantation of lungs. The surgery was conducted at Northwestern Hospital Chicago, where the medical team managed the complex process of replacing four different organs to address the health complications associated with the patient's condition. This event marks a significant clinical milestone in transplant surgery. Coverage from Newswise, the Chicago Tribune, and respiratory-therapy.com emphasizes the rarity and the technical nature of the procedure. These outlets highlight that the case is unique because of the inclusion of retransplanted lungs within a quadruple-organ framework.


ABC7 Chicago specifically reports that Elizabeth Wehrle is thriving following the surgery. The reports collectively stress that this is a first-of-its-kind intervention, focusing on the intersection of cystic fibrosis treatment and the high-risk nature of multi-organ replacement. The coverage points to the specialized capabilities of the surgical team at the Northwestern facility in Chicago. To understand the significance of this event, it is necessary to note the patient's medical history. As reported by the Chicago Tribune, the woman had previously undergone a lung transplant before this quadruple-organ procedure. The presence of cystic fibrosis is a central context for the surgery, as noted by the Chicago Sun-Times and respiratory-therapy.com. The need for a quadruple-organ transplant suggests a level of systemic failure or complication that required a more comprehensive surgical approach than a standard single-organ replacement.


This case illustrates the extreme measures required when previous transplants are no longer sufficient for a patient's survival. Future developments will likely center on the long-term recovery and stability of Elizabeth Wehrle. Based on the provided coverage, observers will be monitoring her progress to see how she continues to thrive after such a complex operation. Because this is cited as the first known instance of a quadruple-organ transplant involving retransplanted lungs, medical professionals may look toward the outcomes of this case to inform future surgical strategies for patients with cystic fibrosis. There is no further information available regarding the specific organs transplanted beyond the lungs or the planned follow-up schedule for the patient.

## Multi-Source Evidence Table
| Source Outlet | Headline | Verification URL |
|---|---|---|
| Newswise | Northwestern Medicine Performs First Known Quadruple-Organ Transplant Involving Retransplanted Lungs - Newswise | [Source Link](https://news.google.com/rss/articles/CBMizwFBVV95cUxOdzRlMHVpSGJkN2FWQWdCS2ZmSW4ydjZldDBwRzBSYWVJcE01ZmhwQTRGWkJkd0FRVlhHWnJxZ2JBT3laWVNDVmRIRGl1WjJ5SXljY2w0TmdYWTRMUHdubTBfMHFUczlfZ0oxUUJvcktTbEFjTDg2UHBqVWJhT0I5Y2lVbWFMZ08wRVJoSk1IaTNaNUQ3UXRRRzZPNFlHRzBWTWIzcFRNVWVfazA5VUhhVUs2ZDUyNVNlci1UWU1jcU1ueWdIU3VCRTNnU042S2PSAc8BQVVfeXFMTnc0ZTB1aUhiZDdhVkFnQktmZkluMnY2ZXQwcEcwUmFlSXBNNWZocEE0RlpCZHdBUVZYR1pycWdiQU95WllTQ1ZkSERpdVoyeUl5Y2NsNE5nWFk0TFB3bm0wXzBxVHM5X2dKMVFCb3JLU2xBY0w4NlBwalViYU9COWNpVW1) |
| respiratory-therapy.com | Retransplanted Lungs Used in CF Quadruple Organ Transplant | [Source Link](https://news.google.com/rss/articles/CBMi5wFBVV95cUxPVXJEUEVKb2Z0VDM0cVVmeUU3dUxJVWxDQW5DVEtXZS1jdm53VUg4Mnl4TTlTYTk0NDNTVXRHQk9ibmF5NGplZlJmVjVGZlFxU2xOSzZXMkV1Y184clFNZkpUYlRJZU1OMG5KM1ROMHVwNkxoUkdTMlRrT2UtTjBJd3RiSkRxbWJLcVl6d09oVlZ4azVUUlU5am0yUkNzTTh2aE5wMmd5X0VtekJTMl9TYk9HSFA1dms3d2hmUFZCY3dCMFdGR0RSWVVLbzk2WmMyRVlJdlpUZ0RxN1c4cTg5Q2lNS0pNV1E?oc=5) |
| Chicago Sun-Times | Woman with cystic fibrosis undergoes 'first-of-its-kind' quadruple-organ transplant at Northwestern | [Source Link](https://news.google.com/rss/articles/CBMi3AFBVV95cUxQRUZlT3N1TjhkOUs5RVpLbS1Da01nNEtOWXhWZU5nZG5sYTM0WW5rakhScW42ZG5GRmZneUl3NDIyQ2hheTNCLXlBOW9aRno4QnBXcWhWX0U5V2RmWGJqQUhIenJBUFZBb2RwczVoRGsyX05PZl91Z2Z4WTdSVFBxWlNrUGdUc1lHdmRLX09lckRKakM2MjFDWmlDZ0JRZkp6WUlCUm9kcjNTTF9UeXJDVXFMSzBKb01wa3FDbUtVQVh1ZXR5OHRuRkdhZUZiOVR5YzhnczhZUHpxcmhJ?oc=5) |
| ABC7 Chicago | Elizabeth Wehrle with cystic fibrosis thrives after quadruple-organ transplant surgery at Northwestern Hospital Chicago | [Source Link](https://news.google.com/rss/articles/CBMi3AFBVV95cUxNbDVyYkVDQTFseGdpdkxpTDU4QWZLR2FDU0tMeW1XSzU3TlktZ2N5U1JXUl9jRFpsRlJWaHNMMVNPTTJrUl9SeGNTQjFmOVBwa2FWb1l5cE9nc29xRl92dHRIWU5adVZhbmc0R09QUmd1WWZweGNoMi1PandEYjZEU1lKbnZ2TmVYVVRtM09STHliSHN1SWgyOEI3blpfcXZodmNXbElodHlpV1MxT0ZqcGRJdFp3aXE3dWxwallIdDR3cTdabnVSTEVvRTZ5UnlxaXdKWlkzRW5GVlZ30gHiAUFVX3lxTFBOd1lzXzVLeEJRc3ZqTWpXSHdjSTZ1TmlBTkE2VnRZSV8wdVNVY1FTT3ZyUHBHUVVPTTAyMWpmNUxtcl94dUM4TjRULUVkQnJlSHFLQUtWV1V2S2ExU0dfTGlXUEh3TFZfV2M5VUpzRWl5YjRGbDZ) |
| Chicago Tribune | Northwestern performs rare quadruple-organ transplant on woman who previously had lung transplant | [Source Link](https://news.google.com/rss/articles/CBMigwFBVV95cUxPZHNySWE1bUlwZUtabE5YLUFRSkNSVHlNSFdVSDJEWGRFWGkwT3ZyM1JtVlljNl9ObEpaZWVBVTBNVFFmcG5ZQ1FrUkQtOVJUeVIyUVhhbllsd3E2WEhhQ1UwT0wyZDZncW1FQ2tLQndaWTl0WGZ2RFduQUdsLWlrSFYwQQ?oc=5) |

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*Canonical Source: https://pulse.byoviral.com/trend/2026-07-14/northwestern-performs-rare-quadruple-organ-transplant-on-woman-who-previously*