# Gene therapy that led to boy’s death had limited efficacy

> **Open Intelligence Dossier** · First detected: 2026-10-28 15:00 UTC · Category: Science

## Multi-Source Evidence Table
| Source Outlet | Headline | Verification URL |
|---|---|---|
| Penn Medicine | Stopping muscular dystrophy with a ‘backup’ protein | [Source Link](https://news.google.com/rss/articles/CBMiiwFBVV95cUxObnBGdXBrVy1NdnhpZEk4Qm0wUHlLMGlZcS1nTmMyT3hEQ2RqbmJHRUpyYm5uamFIMF9wRGFObzZXc3lmVmpiRFdRd0NaalJtLWFLWHBreXl3Zzh2TWZacThiS2JpdTBsRHJXdFg0WU5jMFFxWGd2X0kxa0lwRGRQMXhLcDFncXgwa1lJ?oc=5) |
| CRISPR Medicine News | Single-AAV CRISPR Edits Duchenne Muscle but Exposes Fatal Toxicity | [Source Link](https://news.google.com/rss/articles/CBMipgFBVV95cUxOOTJOSXpQTE11Nl80VjNTRUFaMXZzeVZXUG1lSTV4b2hkSnFSSVE5dlR2NWFCRjZUUW12TzNkUEc5ZHRNb0pRcmFYcVJjSzdDbnBwQmM2Z0NnNWdSSFcxRTZ6M0JzX0JyTHNRcG04aTBBMlppX2F4VE1xRW1XeTZIOWtBeDVKOXdqV2tCaUJ3ZkU0M2E2bEc2MUwxS1BWNlNUWUpLR1hB?oc=5) |
| South China Morning Post | In China gene-editing trial, 2 children improved, 1 died and 1 withdrew | [Source Link](https://news.google.com/rss/articles/CBMivwFBVV95cUxPaHRHcENiakp3LXdsZ2RYWHNEZjBMOXhkMzF2NG1oZmxRbGRZR0tuU3hsejNkd0Z0TkhqSUxoRTk3QjhMa0owSVg0bGxzWl9raVg5eVdmOFg1QzBRb3laU2JsYXJXbGpmYW9CV3ZyOHYwbW9wYTkwY3FERkhyZmRraUhJLUk2R0czcGRKYmxGMTFDN1hCRnQ4bnBBVmlvZ1NnWXFZTS1ZWkQ1TlhRTmJvT2RHRThCZlFTbkl6NWxIVQ?oc=5) |
| Nature | Gene therapy that led to boy’s death had limited efficacy | [Source Link](https://news.google.com/rss/articles/CBMiX0FVX3lxTE81VjBYb1Jfc054NkowRXBWRnN1ekpFUHB4NXpwZnh3d2JhUGc3Z0hsR1lwS1FYY1hsWUczXy1qcHU3bV9MdlZsa1BwU1p2emVCZWxlR3BmLXMzR0w4VHE0?oc=5) |

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*Canonical Source: https://pulse.byoviral.com/trend/2026-10-28/gene-therapy-that-led-to-boy-s-death-had-limited-efficacy*