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▲ Peaking Health

Saturation genome editing of BRCA1 across cell types improves interpretation of variant pathogenicity

4sources
5articles
3velocity
+0%since first seen
24m agofirst detected

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↓ Cooling Health

Domain-alteration chimeras rewire oncogenic complexes in prostate cancer

University of Michigan researchers developed DALTAC-1, a bifunctional small molecule that glues the androgen receptor and p300/CBP together in an abnormal configuration, suppressing prostate tumor growth in preclinical models with roughly 1,000-fold greater potency than separate

6 sources 6 articles v 6 24m ago
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